0320122013201820192020Establishment of a dermatology brandTateyama Pharmaceutical Factory Co., Ltd.Manufacture of pharmaceutical productsTateyama Pharmaceutical Tateyama Pharmaceutical Factory Co., Ltd.Factory Co., Ltd.Maruho DeutschlandMaruho DeutschlandGmbH (Germany)GmbH (Germany)Maruho Medical, Inc. (U.S.)Maruho Medical, Inc. (U.S.)Kose Maruho Pharma Co., Ltd.Kose Maruho Pharma Co., Ltd.Maruho America Inc. (U.S.)Maruho America Inc. (U.S.)Roman Industries Co., Ltd.Roman Industries Co., Ltd.History of the Maruho GroupIn 1990, acquired additional indication of Asteatosis for Hirudoid. Launched numerous products, such as Hirudoid Soft (currently Hirudoid Soft Ointment) and Hirudoid Lotion.Widely accepted by dermatologists as a topical agent for the treatment of psoriasis vulgaris with high safety and effectiveness. This became an opportunity to establish Maruho’s topical drug speciality.The first acne vulgaris treatment agent using benzoyl peroxide as an active ingredient in Japan, able to inhibit bacteria from developing resistance. Developed by Maruho in response to a request from related authorities.The first treatment agent in Japan for infantile hemangioma (strawberry hemangioma), a kind of red birthmark that occurs from the neonatal period to early infancy, developed and launched in response to a request from related authorities.Launched as the world’s first treatment agent against herpes zoster effective when taken once a day.Net sales (Consolidated)(Millions of yen)Maruho Hatsujyo Kogyo Co., Ltd.Manufacture and sales of springs and packaging machinesRoman Industries Co., Ltd.Manufacture and sales of pharmaceutical products Kose Maruho Pharma Co., Ltd.Planning, development, marketing, and sales of over-the-counter (OTC) drugs, quasi-drugs, and cosmetics1996–Blood-flow accelerative/skin-moisturizing agentTreatment agent for keratosis including psoriasis vulgarisLaunched Oxarol Ointment“Hirudoid” series2001–Acne vulgaris treatment agentMaruho Deutschland GmbHDevelopment of pharmaceutical business in Europe Biofrontera AG (Germany)Mainly funding for group companies in the U.S. and Europe that develop and sell pharmaceutical productsMaruho Israel Innovation Fund GmbH & Co. KG (Germany)Investment in pharmaceutical venture companies, etc.Maruho Israel Innovation Labs Ltd. (Israel)Operation and development support of investee companies2015–Infantile hemangioma treatment agentBEPIO Gel2016–Hemangiol Syrup for PediatricMaruho America Inc. (U.S.)Development of pharmaceutical subsidiariesMaruho Medical, Inc. (U.S.)Manufacture and sales of medical affiliates2017–Anti-herpes virus agentAmenalief TabletsConsolidated subsidiariesEquity-method affiliatesMajor Af■liated Companies96,754
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